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Tetrahydrofuran (THF) REACH

- Apr 28, 2018 -

Tetrahydrofuran (THF) is a general purpose, highly volatile organic solvent. It is colorless, water-miscible, mobile liquid. It offers very good solvent power for numerous organic substances and is used as a starting material for various  syntheses.

Tetrahydrofuran(THF) can be recovered easily, without decomposition, from off-gas streams and contaminated solvents, making it suitable for closed-loop processes designed to avoid polution.

The peroxide fraction in fresh Tetrahydrofuran (THF) lies well. However, due to the nature of the product, it may rise during transport, filling, refilling, storage and samples.

Tetrahydrofuran (THF) distilled pure(THF) is a clear, colorless, low-boiling, volatile, polar liquid. It is a cyclic, aliphatic ether with a characteristic odor reminiscent of acetone.


Tetrahydrofuran(THF) distilled pure has many applications as a solvent, reaction medium or starting product for syntheses. Only a few of the many examples of its usefulness are presented below:


Artifical leather: PVC or polyurethane spread-coating systems contain Tetrahydrofuran(THF) alone or in blends with other solvents.

Magnetic tapes: The abrasion resistance of video, computer or audio tapes can be improved by applying coatings derived from polyurethane or PVC in which the solvent phase is a blend of tetrahydrofuan(THF) and toluene. 

Cellophane: The mechanical strength, impermeability to water vapor, heatsealability and printability of cellophane can be improved by applying coatings formulated from poly(vinylidene chloride)(PVDC), in which the solvent phase is a blend of tetrahydrofuran(THF) and toluene


Tetrahydrofuran(THF) is suitable for the production of PVC adhesives for rigid PVC. It is used as a swelling agent for bonding plasticized PVC film and for fabricating PVC pipe systmes. In both cases, the evaporation rate can be regulated by blending the Tetrahydrofuran(THF) with another solvent, such as cyclohexanone.

Specialty coating systems

By virtue of its excellent solvent poser, tetrahydrofuran(THF) allows the preparation of highly concentrated solutions of various polymers. These solutions can be diluted to the appropriate final concentration by adding thinners. Although tetrahydrofuran(THF) evaporates rapidly, films formed from its solutions have very minimal tendency toward blushing during drying.

Reatcion medium

Tetrahydrofuran(THF) is a reaction medium, used primarily by the pharmaceutical industry, eg. in Grignard syntheses or lithium aluminum hydride reductions. In fact, it is the only medium in which many Grignard compounds can be obtained. By virtue of its good solvent power for alkali metals, Tetrahydrofuran(THF) is a useful reaction medium for the production of organometallic compounds.

Anionic polymerization reactions can be carried out in Tetrahydrofuran(THF) as well.


Some drugs, e.g. alkaloids, can be obtained in the pure form from their natural or synthetic precursors by extraction with Tetrahydrofuran(THF). Also impurities such as fat, wax or substances with a high molecular mass can be removed from compounds that are insoluble in Tetrahydrofuran(THF).

for Tetrahydrofuran(THF), we have REACH registration, for price or more information,  pls feel free to contact with me at  vicky@gpcchem.com


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